O. N. Yogurtcu

NERDSS simulates multibody self-assembly processes by integrating reaction-diffusion with rule-based models, enabling comparison with experimental data on clathrin-mediated endocytosis and viral lattice assembly.

This paper introduces an implicit lipid model for efficient reaction-diffusion simulations of protein binding to surfaces of arbitrary topology, showing agreement with explicit lipid models and enabling stable multi-protein complex formation.

The paper quantifies how membrane localization enhances protein-protein interactions by reducing search space, showing significant increases in effective affinity for endocytic proteins.