Author

O. Porrua

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Organism:yeast· 1

Frequent Co-Authors

C. W. Mueller· 1 shared D. Libri· 1 shared H. Groetsch· 1 shared J. Xie· 1 shared M. Girbig· 1 shared M. Sebesta· 1 shared R. Stefl· 1 shared V. Klapstova· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

C. W. Mueller

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2 papers

Recent·Most cited

Human senataxin is a bona fide R-loop resolving enzyme and transcription termination factor

Z. Hasanova, V. Klapstova, O. Porrua, R. Stefl, M. Sebesta

This study characterizes Senataxin as an R-loop resolving helicase and transcription termination factor, revealing its biochemical properties and the impact of disease-associated mutations.

bioRxiv · Aug 25, 2022Biochemistry

Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly-dT termination signals

M. Girbig, J. Xie, H. Groetsch, D. Libri, O. Porrua, C. W. Mueller

The paper reports cryo-EM structures of the yeast Pol III pre-termination complex and identifies key residues involved in poly-dT termination signal recognition and pausing.

bioRxiv · Feb 28, 2022Biochemistry