Author

R. Stefl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

M. Sebesta· 2 shared A. Akalin· 1 shared A. Baazaoui· 1 shared A. Kasiliauskaite· 1 shared A. Stark· 1 shared A. Vlasova· 1 shared C. Bernecky· 1 shared D. Slade· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

M. Sebesta

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural and functional characterisation of the interaction between the influenza A virus RNA polymerase and the CTD of host RNA Polymerase II

J. Keown, A. Baazaoui, M. Sebesta, R. Stefl, L. Carrique, E. Fodor, J. Grimes

This study characterizes the structural and functional interaction between influenza A virus RNA polymerase and host RNA Polymerase II CTD, identifying key residues and their roles in transcription and replication.

bioRxiv · Nov 29, 2023 · PreprintMicrobiology

Human senataxin is a bona fide R-loop resolving enzyme and transcription termination factor

Z. Hasanova, V. Klapstova, O. Porrua, R. Stefl, M. Sebesta

This study characterizes Senataxin as an R-loop resolving helicase and transcription termination factor, revealing its biochemical properties and the impact of disease-associated mutations.

bioRxiv · Aug 25, 2022Biochemistry

PHF3 regulates neuronal gene expression through the new Pol II CTD reader domain SPOC

L.-M. Appel, V. Franke, M. Bruno, I. Grishkovskaya, A. Kasiliauskaite, U. E. Schoeberl, M. G. Puchinger, S. Kostrhon, E. Beltzung, K. Mechtler, G. Lin, A. Vlasova, M. Leeb, R. Pavri, A. Stark, , D. Slade

This study identifies PHF3 as a CTD-binding factor that regulates neuronal gene expression by inhibiting Pol II elongation and mRNA stability.

bioRxiv · Feb 11, 2020Biochemistry