KDM2B Silencing Elicits a Paracrine Mechanism Which Destabilizes SLUG, Promoting Differentiation of Basal-Like Breast Cancer Cells.
E.-A. Fraile, B. Soysal, V. Anastas, Z. T. Soysal, O. Serebrennikova, M. D. Paraskevopoulou, E. Chavdoula, P. N. Tsichlis
This paper shows that silencing KDM2B triggers a paracrine mechanism that inactivates GSK3, leading to SLUG degradation and differentiation of basal-like breast cancer cells.
bioRxiv · May 21, 2020 · PreprintCancer Biology