Crosstalk between β-catenin and WT1 signalling activity in acute myeloid leukemia
M. Wagstaff, O. Tsaponina, G. Caalim, H. Greenfield, L. Milton-Harris, E. J. Mancini, A. Blair, K. J. Heesom, A. Tonks, R. L. Darley, S. G. Roberts, R. G. Morgan
This study identifies a novel interaction between β-catenin and WT1 in AML, showing they influence each other's expression and signaling activity, which may inform therapeutic strategies.
bioRxiv · Nov 6, 2021Cancer Biology