Engineering genetically-encoded synthetic biomarkers for breath-based cancer detection
O. Vermesh, A. D'Souza, I. S. Alam, M. Wardak, T. McLaughlin, F. El Rami, A. Sathirachinda, J. C. Bell, M. L. James, S. S. Hori, E. R. Gross, S. S. Gambhir
This paper develops a breath-based cancer detection system using engineered D-limonene production in tumors, achieving high sensitivity and specificity in mice and predicting human tumor detection limits.
bioRxiv · Sep 1, 2021 · PreprintBioengineering