Author

I. S. Alam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:drug response / drug discovery· 3 Assay:imaging· 3 Research Focus:cell type annotation· 2 Assay:fluorescence / live-cell microscopy· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:differential expression· 1

Frequent Co-Authors

S. S. Gambhir· 3 shared J. Rao· 2 shared A. D'Souza· 1 shared A. Danckaert· 1 shared A. Kamau· 1 shared A. Sathirachinda· 1 shared A. Zlitni· 1 shared C. Bowler· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersBioengineering

S. S. Gambhir

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Highly Excretable Gold Supraclusters for Translatable In Vivo Raman Imaging of Tumors

J. H. Yu, M. S. Jeong, E. O. Cruz, I. S. Alam, S. K. Tumbale, A. Zlitni, S. Y. Lee, Y. I. Park, K. Ferrara, S.-H. Kwon, S. S. Gambhir, J. Rao

This paper develops excretable gold supraclusters for in vivo Raman imaging of tumors, showing high excretion rates and effective tumor detection in mice.

bioRxiv · Oct 18, 2022 · PreprintBioengineering

Multi-parameter optical imaging of immune cell activity in chimeric antigen receptor T-cell and checkpoint blockade therapies

J. Xie, F. E. Rami, K. Zhou, F. Simonetta, Z. Chen, X. Zheng, M. Chen, P. B. Balakrishnan, S.-Y. Dai, S. Murty, I. S. Alam, J. Baker, R. S. Negrin, S. S. Gambhir, J. Rao

The paper develops a small molecule for imaging immune cell activity in cancer immunotherapies and demonstrates its utility in predicting treatment outcomes.

bioRxiv · Oct 11, 2021 · PreprintImmunology

Engineering genetically-encoded synthetic biomarkers for breath-based cancer detection

O. Vermesh, A. D'Souza, I. S. Alam, M. Wardak, T. McLaughlin, F. El Rami, A. Sathirachinda, J. C. Bell, M. L. James, S. S. Hori, E. R. Gross, S. S. Gambhir

This paper develops a breath-based cancer detection system using engineered D-limonene production in tumors, achieving high sensitivity and specificity in mice and predicting human tumor detection limits.

bioRxiv · Sep 1, 2021 · PreprintBioengineering

Metabolic Architecture of the Deep Ocean Microbiome

S. G. Acinas, P. Sanchez, G. Salazar, F. M. Cornejo-Castillo, M. Sebastian, R. Logares, S. Sunagawa, P. Hingamp, H. Ogata, G. Lima-Mendez, S. Roux, J. M. Gonzalez, J. M. Arrieta, I. S. Alam, A. Kamau, , J. M. Gasol

The paper analyzes deep ocean microbial metagenomes to reveal functional diversity and metabolic strategies in the dark ocean.

bioRxiv · May 13, 2019Microbiology

Imaging of red-shifted photons from bioluminescent tumours using fluorescence by unbound excitation from luminescence

F. Sonego, S. Bouccara, T. Pons, N. Lequeux, A. Danckaert, J.-Y. Tinevez, I. S. Alam, S. L. Shorte, R. Tournebize

The paper applies FUEL to enhance bioluminescence imaging for deeper tumour detection in two models.

bioRxiv · Sep 28, 2018Bioengineering