Author

Olena Lykhmus

Palladin Institute of Biochemistry

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Neuroscience· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Elizabeta Zirdum· 1 shared Kateryna Uspenska· 1 shared Lyudmyla Koval· 1 shared Maryna V. SkokiD· 1 shared Olena KalashnykiD· 1 shared Olga GaraschukiD· 1 shared Wen-Yu TzengiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Elizabeta Zirdum

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1 paper

Recent·Most cited

Impairment of brain function in a mouse model of Alzheimer's disease during the pre-depositing phase: the role of alpha7 nicotinic acetylcholine receptors

Olena Lykhmus, Wen-Yu Tzeng, Lyudmyla Koval, Kateryna Uspenska, Elizabeta Zirdum, Olena Kalashnyk, Olga Garaschuk, Maryna V. Skok

This study shows that in a mouse model of Alzheimer's disease, before amyloid deposition, there are increased inflammatory markers, reduced nicotinic acetylcholine receptors, and impaired memory, which can be mitigated by targeting alpha7 nAChRs.

Biomedicine & Pharmacotherapy · Aug 7, 2024Peer-reviewedNeuroscience