Author

Brenna S. McCauley

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:C. elegans· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Weiwei DangiD· 2 shared Aashna Lamba· 1 shared Adarsh RajeshiD· 1 shared Adrianna Abele· 1 shared Alexandre R. ColasiD· 1 shared Anagha J. DeshpandeiD· 1 shared Aniruddha J. DeshpandeiD· 1 shared Caroline KumstaiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenomics

Weiwei DangORCID

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Author profile →

3 papers

Recent·Most cited

Nucleosome stability safeguards cell identity, stress resilience and healthy aging

Hiroshi Tanaka, Brenna S. McCauley, Clara Guida, Xue Lei, Sha Li, Tatiana M. Moreno, K'leigh Guillotte, Zong Ming Chua, Adrianna Abele, Aashna Lamba, Rouven Arnold, Adarsh Rajesh, Marcos G. Teneche, Laurence Haddadin, Anagha J. Deshpande, , Peter D. Adams

The paper shows that reduced nucleosome stability impairs cell identity, stress resilience, and healthy aging across species.

bioRxiv · Sep 17, 2025 · PreprintGenomics

Yeast EndoG prevents genome instability by degrading cytoplasmic DNA

Yang Yu, Xin Wang, Jordan Fox, Ruofan Yu, Pilendra Kumar Thakre, Brenna S. McCauley, Nicolas Nikoloutsos, Qian Li, P. J. Hastings, Weiwei Dang, Kaifu Chen, Grzegorz Ira

The paper investigates the role of yeast EndoG (Nuc1) in preventing genome instability by degrading cytoplasmic DNA and regulating its transfer to the nucleus.

Nature Communications · Sep 3, 2024Peer-reviewedGenetics

Systematic comparison of developmental GRNs explains how novelty is incorporated in early development

Gregory A. Cary, Brenna S. McCauley, Olga R. Zueva, Joseph Pattinato, William J.R. Longabaugh, Veronica F. Hinman

The paper compares developmental GRNs to show how novelty is incorporated while maintaining network stability during early development.

Nature Communications · Dec 4, 2020Peer-reviewedDevelopmental Biology