Measles vaccine attenuation comprises innate immune cell infection and interferon responses
Felix G M Andres, Sebastian Parusel, Oliver Siering, Francisco M. Acosta, Dominic A. Skeele, Katayoun Ayasoufi, Roberto Cattaneo, Bevan Sawatsky, Christian Karl Pfaller
This study identifies that measles vaccine attenuation involves enhanced infection of innate immune cells and strong interferon responses that limit viral replication.
bioRxiv · Jun 9, 2025 · PreprintImmunology