Author

Sebastian Parusel

Mayo Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Christian Karl PfalleriD· 2 shared Felix G M AndresiD· 2 shared Oliver Siering· 2 shared Bevan SawatskyiD· 1 shared Biruhalem TayeiD· 1 shared Christine HuntiD· 1 shared Csaba MiskeyiD· 1 shared Dominic A. Skeele· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Christian Karl PfallerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Measles vaccine attenuation comprises innate immune cell infection and interferon responses

Felix G M Andres, Sebastian Parusel, Oliver Siering, Francisco M. Acosta, Dominic A. Skeele, Katayoun Ayasoufi, Roberto Cattaneo, Bevan Sawatsky, Christian Karl Pfaller

This study identifies that measles vaccine attenuation involves enhanced infection of innate immune cells and strong interferon responses that limit viral replication.

bioRxiv · Jun 9, 2025 · PreprintImmunology

TSniffer: Unbiased de novo identification of RNA editing sites and quantification of editing activity in RNA-seq data

Maike Herrmann, Yvonne Krebs, Francisco M Acosta, Sebastian Parusel, Oliver Siering, Felix G M Andres, Biruhalem Taye, Csaba Miskey, Christian Karl Pfaller

TSniffer identifies RNA editing sites and quantifies editing activity in RNA-seq data, revealing widespread ADAR-mediated editing in mammals.

bioRxiv · Nov 13, 2024 · PreprintBioinformatics

Spinal Microglia Contribute to Sustained Inflammatory Pain via Amplifying Neuronal Activity

Nan Gu, Min‐Hee Yi, Madhuvika Murugan, Manling Xie, Sebastian Parusel, Jiyun Peng, Ukpong B. Eyo, Christine Hunt, Hailong Dong, Long‐Jun Wu

This study shows spinal microglia amplify neuronal activity in inflammatory pain via the P2Y12 receptor, suggesting a therapeutic target for pain management.

Molecular Brain · Oct 26, 2022Peer-reviewedNeuroscience