Use of CRISPR/Cas9 Gene Targeting to Conditionally Delete Glucocorticoid Receptors in Rat Brain
Jessie R. Scheimann, Rachel D. Moloney, Parinaz Mahbod, Rachel L. Morano, Maureen E. Fitzgerald, Olivia Hoskins, Benjamin A. Packard, Yueh‐Chiang Hu, James P. Herman
This study uses CRISPR/Cas9 to create a conditional GR knockout in rats, showing sex-specific behavioral effects of GR deletion in the prelimbic cortex.
bioRxiv · Feb 27, 2019 · PreprintNeuroscience