NEIL1 and NEIL2 DNA glycosylases regulate anxiety and learning in a cooperative manner
Gunn A. Hildrestrand, Veslemøy Rolseth, Nicolas Kunath, Rajikala Suganthan, Vidar Jensen, Anna Maria Bugaj, Marion Silvana Fernández-Berrocal, Sunniva Bøe Sikko, Susanne Vetlesen, Anna Kuśnierczyk, Ann-Karin Hardie Olsen, Kristine B. Gützkow, Alexander D. Rowe, Wei Wang, Olve Moldestad, , Magnar Bjørås
This study shows that NEIL1 and NEIL2 DNA glycosylases work together to regulate anxiety and learning in mice, despite not affecting oxidative DNA damage levels.
bioRxiv · Feb 8, 2021 · PreprintMolecular Biology