Nicolas Kunath

Ogg1 regulates context-dependent glial states in Alzheimer's disease

This study shows Ogg1 has opposing effects on glial states in Alzheimer's disease, improving memory and reducing amyloid burden in a mouse model while impairing memory under physiological conditions.

Sustained polyphasic sleep restriction abolishes human growth hormone release

This study examines the effects of sustained polyphasic sleep restriction on human growth hormone release and other physiological and cognitive measures.

DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons

This study shows NEIL3 affects spatial stability in hippocampal neurons by altering transcription of NMDA receptor subunits and immediate early genes.

NEIL1 and NEIL2 DNA glycosylases regulate anxiety and learning in a cooperative manner

This study shows that NEIL1 and NEIL2 DNA glycosylases work together to regulate anxiety and learning in mice, despite not affecting oxidative DNA damage levels.

Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression

The paper shows AAG associates with transcription elongation to coordinate DNA repair with gene expression, revealing roles of aberrantly methylated bases in gene regulation.