Different Purkinje cell pathologies cause specific patterns of progressive ataxia in mice
Dick Jaarsma, María B. Birkisdóttir, Randy van Vossen, Demi W.G.D. Oomen, Oussama Akhiyat, Wilbert P. Vermeij, Sebastiaan K. E. Koekkoek, Chris I. De Zeeuw, Laurens W. J. Bosman
This study shows that different Purkinje cell pathologies in mice lead to distinct patterns of progressive gait ataxia, highlighting the importance of pathological mechanisms in disease progression.
Neurobiology of Disease · Jan 28, 2024Peer-reviewedNeuroscience