Sebastiaan K. E. Koekkoek

Mobile Human Brain Imaging using Functional Ultrasound

This paper demonstrates the feasibility of functional ultrasound imaging (fUSi) for monitoring brain activity during real-world activities like walking over 20 months.

Acute Aerobic Exercise Enhances Associative Learning in Active but not Sedentary Individuals

This study shows acute aerobic exercise improves eyeblink conditioning in active individuals but not sedentary ones.

Different Purkinje cell pathologies cause specific patterns of progressive ataxia in mice

This study shows that different Purkinje cell pathologies in mice lead to distinct patterns of progressive gait ataxia, highlighting the importance of pathological mechanisms in disease progression.

A long-deletion mouse model of Williams syndrome reveals Ncf1-dependent modulation of vascular and neural phenotypes

This paper develops a long-deletion mouse model of Williams syndrome to study vascular and neural phenotypes, finding that Ncf1 modulates both cardiovascular and neuropsychological symptoms.

Eyeblink conditioning performance and brain-wide C-fos expression in male and female mice

This study examines individual differences in eyeblink conditioning performance and brain-wide C-fos expression in male and female mice across strains, finding comparable variability and correlations between locomotion and learning.

Pigs as a new behavioral model for studying Pavlovian eyeblink conditioning

This study develops and validates an eyeblink conditioning paradigm in young pigs, demonstrating their capability to perform cerebellar classical association learning.