Author

Dick Jaarsma

Erasmus MCORCID 0000-0002-0519-2940Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Chris I. De ZeeuwiD· 2 shared Laurens W. J. BosmaniD· 2 shared Sebastiaan K. E. KoekkoekiD· 2 shared Bastian S. GenerowicziD· 1 shared Changyang ZhouiD· 1 shared Danique Broere· 1 shared Demi W.G.D. Oomen· 1 shared Emma Kretschmann· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Chris I. De ZeeuwORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Different Purkinje cell pathologies cause specific patterns of progressive ataxia in mice

Dick Jaarsma, María B. Birkisdóttir, Randy van Vossen, Demi W.G.D. Oomen, Oussama Akhiyat, Wilbert P. Vermeij, Sebastiaan K. E. Koekkoek, Chris I. De Zeeuw, Laurens W. J. Bosman

This study shows that different Purkinje cell pathologies in mice lead to distinct patterns of progressive gait ataxia, highlighting the importance of pathological mechanisms in disease progression.

Neurobiology of Disease · Jan 28, 2024Peer-reviewedNeuroscience

A long-deletion mouse model of Williams syndrome reveals Ncf1-dependent modulation of vascular and neural phenotypes

Laurens W. J. Bosman, Hamid el Azzouzi, Lieke Kros, Nicole van Vliet, Yanto R. Ridwan, Stéphanie Dijkhuizen, Erika Sabel-Goedknegt, Bastian S. Generowicz, Martijn C. Sierksma, Dick Jaarsma, Manuele Novello, M. W. C. Snoeren, Emma Kretschmann, Danique Broere, Rocco Caliandro, , Chris I. De Zeeuw

This paper develops a long-deletion mouse model of Williams syndrome to study vascular and neural phenotypes, finding that Ncf1 modulates both cardiovascular and neuropsychological symptoms.

bioRxiv · Oct 30, 2023 · PreprintSystems Biology