Author

Owen Mcmanus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:electronic health records· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Alfred L. GeorgeiD· 1 shared Chinwendu Obi Obasi· 1 shared Diana Jazmin Ixmatlahua RiberaiD· 1 shared Enrique Rojas· 1 shared Graham T. DempseyiD· 1 shared Karthiayani Harikrishnan· 1 shared Linda LauxiD· 1 shared Luis A. Williams· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alfred L. GeorgeORCID

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1 paper

Recent·Most cited

Excitatory Dysfunction and Phenotypic Rescue in a Human Neuronal Model of SCN2A-Related Disorders

Sashmita Panda, Diana Jazmin Ixmatlahua Ribera, Luis A. Williams, Sheng Tang, Karthiayani Harikrishnan, Vaibhav Joshi, Steven J. Ryan, Chinwendu Obi Obasi, Linda Laux, Enrique Rojas, Owen Mcmanus, Graham T. Dempsey, Alfred L. George, Scott K. Adney

This study examines the impact of a SCN2A pathogenic variant in human neurons using electrophysiology and machine learning, showing that sodium channel blockers can restore normal function.

bioRxiv · May 19, 2026 · PreprintNeuroscience