Essential role of the CCL2-CCR2 axis in Mayaro virus-induced disease
F. M. Santos, V. C. Melo, S. Araujo, C. D. F. Sousa, T. P. Moreira, M. R. Goncalves, A. C. Santos, H. A. Seabra, P. A. C. Costa, B. R. Barrioni, P. B. Souza, M. d. M. Pereira, M. L. Nogueira, D. G. Souza, P. P. Guimaraes, , V. V. Costa
This study shows that the CCL2-CCR2 axis drives inflammation and bone loss in Mayaro virus infection by recruiting macrophages and promoting osteoclastogenesis.
bioRxiv · Jul 21, 2023Cell Biology