Author

P. Brugarolas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

J. E. Sanchez-Rodriguez· 2 shared S. Rodriguez-Rangel· 2 shared Y. Sun· 2 shared A. D. Bravin· 1 shared K. M. Ramos-Torres· 1 shared K. Ramos-Torres· 1 shared L. L. Zhang· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 12 mutual co-author links

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2 shared papersPharmacology & Toxicology

J. E. Sanchez-Rodriguez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chemical and biophysical characterization of novel potassium channel blocker 3-fluoro-5-methylpyridin-4-amine

Y. Sun, S. Rodriguez-Rangel, L. L. Zhang, J. E. Sanchez-Rodriguez, P. Brugarolas

This paper characterizes 5Me3F4AP, a novel K+ channel blocker with improved physicochemical properties and stability compared to existing PET tracers for demyelinated lesion imaging.

bioRxiv · Aug 8, 2023Pharmacology & Toxicology

Metabolic Stability of the Demyelination PET tracer 3F4AP and Identification of its Metabolites

Y. Sun, K. Ramos-Torres, P. Brugarolas

This study investigates the metabolism of the PET tracer [18F]3F4AP, identifies its metabolites, and evaluates the effect of deuteration on its stability.

bioRxiv · Sep 27, 2022Biochemistry

Structure-activity relationship studies of three novel 4-aminopyridine K+ channel blockers

S. Rodriguez-Rangel, A. D. Bravin, K. M. Ramos-Torres, P. Brugarolas, J. E. Sanchez-Rodriguez

This study evaluates three novel 4-aminopyridine derivatives as potential PET imaging and therapeutic agents for KV1 channel blockade in multiple sclerosis.

bioRxiv · Aug 11, 2019Biophysics