Author

J. E. Sanchez-Rodriguez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

P. Brugarolas· 2 shared S. Rodriguez-Rangel· 2 shared A. D. Bravin· 1 shared G. A. Mendez-Maldonado· 1 shared I. L. Gonzalez-Hernandez· 1 shared J. Arreola· 1 shared J. J. De Jesus-Perez· 1 shared K. M. Ramos-Torres· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPharmacology & Toxicology

P. Brugarolas

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Author profile →

3 papers

Recent·Most cited

Chemical and biophysical characterization of novel potassium channel blocker 3-fluoro-5-methylpyridin-4-amine

Y. Sun, S. Rodriguez-Rangel, L. L. Zhang, J. E. Sanchez-Rodriguez, P. Brugarolas

This paper characterizes 5Me3F4AP, a novel K+ channel blocker with improved physicochemical properties and stability compared to existing PET tracers for demyelinated lesion imaging.

bioRxiv · Aug 8, 2023Pharmacology & Toxicology

ELECTRO-STERIC MECHANISM OF CLC-2 CHLORIDE CHANNEL ACTIVATION

J. J. De Jesus-Perez, G. A. Mendez-Maldonado, I. L. Gonzalez-Hernandez, V. De la Rosa, R. Gastelum-Garibaldi, J. E. Sanchez-Rodriguez, J. Arreola

This study identifies the electro-steric mechanism of CLC-2 chloride channel activation through homology modeling, molecular dynamics simulations, and functional experiments.

bioRxiv · Jun 12, 2020 · PreprintPhysiology

Structure-activity relationship studies of three novel 4-aminopyridine K+ channel blockers

S. Rodriguez-Rangel, A. D. Bravin, K. M. Ramos-Torres, P. Brugarolas, J. E. Sanchez-Rodriguez

This study evaluates three novel 4-aminopyridine derivatives as potential PET imaging and therapeutic agents for KV1 channel blockade in multiple sclerosis.

bioRxiv · Aug 11, 2019Biophysics