Site-specific proximity labeling at single residue resolution for identification of protein partners in vitro and on cells
T. G. Bartholow, P. Burroughs, S. K. Elledge, J. R. Byrnes, L. L. Kirkemo, V. Garda, K. K. Leung, J. A. Wells
This paper optimizes a high-resolution proximity labeling method to identify protein partners of HER2 on cells and in vitro, finding 20 high-confidence neighbors enriched compared to non-specific labeling.
bioRxiv · Jul 27, 2023 · PreprintBiochemistry