Hotspot Dosages of Most Rapid Antibiotic Resistance Evolution
R. C. Reding Roman, P. C. Catalan, G. Jansen, P. Rosenstiel, H. Schulenburg, I. Gudelj, R. E. Beardmore
This study investigates how antibiotic resistance evolves in E. coli under varying erythromycin dosages, finding that resistance increases most rapidly just below the minimal inhibitory concentration.
bioRxiv · Dec 6, 2019Evolutionary Biology