AP2A1 is upregulated upon replicative senescence of human fibroblasts to strengthen focal adhesions via integrin β1 translocation along stress fibers
P. Chantachotikul, S. Liu, K. Furukawa, S. Deguchi
The paper identifies AP2A1 upregulation in senescent human fibroblasts, which strengthens focal adhesions via integrin β1 translocation along stress fibers, maintaining large cell size.
bioRxiv · Aug 19, 2023 · PreprintCell Biology