Author

P. Delfino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Scarpa· 3 shared E. Fiorini· 3 shared F. Lupo· 3 shared R. T. Lawlor· 3 shared V. Corbo· 3 shared C. Carbone· 2 shared C. Neander· 2 shared C. Vicentini· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Scarpa

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Author profile →

3 papers

Recent·Most cited

Differential Activity of MAPK signalling Defines Fibroblast Subtypes in Pancreatic Cancer

L. Veghini, D. Pasini, P. Delfino, V. Corbo, E. Fiorini, F. Lupo, M. Bevere, C. Luchini, R. T. Lawlor, A. Scarpa, P. F.-Y. Cheung, J. T. Siveke, C. Vicentini, D. Filippini, S. L. D'Agosto, , R. Fang

This study identifies MAPK signalling as defining fibroblast subtypes in pancreatic cancer, linking MAPKhigh CAFs to poor prognosis and immune evasion.

bioRxiv · Oct 30, 2023Cancer Biology

The axon guidance cue SEMA3A promotes the aggressive phenotype of basal-like PDAC

F. Lupo, F. Pezzini, E. Fiorini, A. Adamo, L. Veghini, M. Bevere, C. Frusteri, P. Delfino, S. D'Agosto, S. Andreani, G. Piro, A. Malinova, F. De Sanctis, D. Pasini, R. T. Lawlor, , V. Corbo

This study shows SEMA3A promotes aggressive basal-like PDAC by enhancing metastasis and modulating the tumor microenvironment through macrophage polarization and T cell exclusion.

bioRxiv · Feb 25, 2023Cancer Biology

MAP Kinase inhibition reshapes tumor microenvironment of mouse pancreatic cancer by depleting anti-inflammatory macrophages

P. Delfino, C. Neander, D. Filippini, S. D'Agosto, C. Vicentini, E. Fiorini, F. Lupo, C. Fiorini, B. Rusev, G. Temgue Tane, F. De Sanctis, M. Simbolo, S. Ugel, V. Bronte, M. Fassan, , V. Corbo

This study shows that MEK inhibition in mouse pancreatic cancer reduces anti-inflammatory macrophages and enhances gemcitabine efficacy by altering the tumor microenvironment.

bioRxiv · Sep 8, 2019 · PreprintCancer Biology