Gfi1-expressing Paneth cells revert to stem cells following intestinal injury
M.-S. Chen, Y.-H. Lo, J. Butkus, W. Zou, Y.-J. Tseng, H.-I. Jen, S. Patel, A. Groves, M. Estes, E. Sahin, M. Frey, P. Dempsey, N. Shroyer
This study shows that Gfi1-expressing secretory cells can revert to stem cells after intestinal injury, with PI3kinase/AKT and WNT signaling enhancing this process.
bioRxiv · Jul 16, 2018 · PreprintCell Biology