Single-molecule imaging of cytoplasmic dynein in cellulo reveals the mechanism of motor activation and cargo movement
N. A. Tirumala, G. M. I. Redpath, N. Kapoor-Kaushik, N. Ariotti, P. Dolai, K. V. Kumar, V. Ananthanarayanan
This study uses single-molecule imaging to reveal how dynein activation and cargo movement occur through stochastic interactions and dynamic binding kinetics.
bioRxiv · Apr 5, 2021Cell Biology