Cell BiologybioRxiv
Single-molecule imaging of cytoplasmic dynein in cellulo reveals the mechanism of motor activation and cargo movement
N. A. Tirumala, G. M. I. Redpath, N. Kapoor-Kaushik…·V. Ananthanarayanan
This study uses single-molecule imaging to reveal how dynein activation and cargo movement occur through stochastic interactions and dynamic binding kinetics.
DOI 10.1083/jcb.202210026