Author

P. Dunbar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

A. Hohmann· 1 shared A. Vu· 1 shared C. Bullock· 1 shared C. Calnan· 1 shared C. Dugopolski· 1 shared C. P. Reynolds· 1 shared C. Wrockage· 1 shared D. M. Booth· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

A. Hohmann

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Rational design of a SOCS1-edited tumor infiltrating lymphocyte therapy for solid tumors using CRISPR/Cas9 screens

M. R. Schlabach, S. Lin, Z. Collester, C. Wrockage, S. Shenker, C. Calnan, T. Xu, H. Gannon, L. Williams, F. Thompson, P. Dunbar, R. LaMothe, T. E. Garrett, N. Colletti, A. Hohmann, , M. J. Benson

This study uses CRISPR/Cas9 screens to identify SOCS1 as a target for enhancing T cell therapy, leading to the development of an engineered TIL therapy with improved anti-tumor function.

bioRxiv · Sep 5, 2023 · PreprintImmunology

REDUCED ER-MITOCHONDRIA CONNECTIVITY PROMOTES NEUROBLASTOMA MULTIDRUG RESISTANCE

J. Coku, D. M. Booth, J. Skoda, M. C. Pedrotty, J. Vogel, K. Liu, A. Vu, E. L. Carpenter, J. C. Ye, M. A. Chen, P. Dunbar, E. Scadden, E. Nakamaru-Ogiso, Y. Li, K. C. Goldsmith, , M. D. Hogarty

The paper identifies reduced ER-mitochondria contacts as a mechanism promoting neuroblastoma multidrug resistance by impairing Ca2+ transfer and apoptosis.

bioRxiv · Mar 1, 2021Cancer Biology