Author

P. E. Polderman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. M. T. Burgering· 3 shared T. B. Dansen· 3 shared D. M. K. van Soest· 2 shared S. De Henau· 2 shared L. J. M. Bruurs· 1 shared M. H. van Triest· 1 shared S. Zwakenberg· 1 shared T. Shi· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCell Biology

B. M. T. Burgering

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3 papers

Recent·Most cited

Direct quantification of chemogenetic H2O2 production in live human cells.

W. T. F. den Toom, D. M. K. van Soest, P. E. Polderman, M. H. van Triest, L. J. M. Bruurs, B. M. T. Burgering, S. De Henau, T. B. Dansen

This paper introduces an assay to directly quantify DAAO-mediated H2O2 production in live human cells and compares it to mitochondrial respiration.

bioRxiv · May 3, 2023Cell Biology

Mitochondrial H2O2 release does not directly cause genomic DNA damage.

D. M. K. van Soest, P. E. Polderman, W. T. den Toom, S. Zwakenberg, S. De Henau, B. M. T. Burgering, T. B. Dansen

This study shows that mitochondrial H2O2 release does not directly cause genomic DNA damage, as it instead triggers ferroptosis and prevents mutation propagation.

bioRxiv · Mar 29, 2023Cell Biology

DNA damage and oxidizing conditions activate p53 through differential upstream signaling pathways.

T. Shi, P. E. Polderman, B. M. T. Burgering, T. B. Dansen

The paper investigates how oxidizing conditions activate p53 through two distinct pathways: DNA damage response and stress-activated kinases, showing they can operate independently.

bioRxiv · Sep 13, 2020Cell Biology