Evaluating aroA gene essentiality and EPSP synthase vulnerability in Mycobacterium smegmatis under different nutritional conditions
M. A. Duque-Villegas, B. L. Abbadi, P. R. Romero, L. Galina, P. F. Dalberto, V. S. Rodrigues-Junior, C. D. Roth, R. S. Rambo, E. V. de Souza, M. A. Perello, P. Machado, L. A. Basso, C. V. Bizarro
This study evaluates the essentiality of the aroA gene and vulnerability of its enzyme EPSPS in Mycobacterium smegmatis under different nutritional conditions using gene knockout, knockdown, and kinetic assays.
bioRxiv · Mar 2, 2020 · PreprintMicrobiology