P. Gerwins

Inhibiting endoplasmic reticulum stress decreases tumor burden in a mouse model for hepatocellular carcinoma.

The paper shows that inhibiting IRE1 reduces tumor burden in a mouse HCC model by blocking stellate cell activation and tumor cell proliferation.

Fibrin fragment E potentiates TGF-β-induced myofibroblast activation and recruitment

This study shows that fibrin fragment E (FnE) attracts fibroblasts and enhances TGF-β-induced myofibroblast formation, contributing to fibrosis.