Distribution and vulnerability of transcriptional outputs across the genome in Myc-amplified medulloblastoma cells
R. Yang, W. Wang, M. Dong, K. Roso, P. Greer, X. Bao, C. J. Pirozzi, D. D. Bigner, H. Yan, D. M. Ashley, F. Zou, V. Zhabotynsky, Y. He
This study examines the distribution of transcriptional outputs in Myc-amplified medulloblastoma cells and identifies IMPDHs as a therapeutic target.
bioRxiv · Jun 7, 2021 · PreprintCancer Biology