Pressure and curvature control of contact inhibition in epithelia growing under spherical confinement
I. Di Meglio, A. Trushko, P. Guillamat, C. Blanch-Mercader, A. Roux
This study shows that epithelial proliferation is regulated by tissue-level pressure via the β-catenin pathway and local curvature changes via the YAP/TAZ pathway under spherical confinement.
bioRxiv · Jun 17, 2021 · PreprintCell Biology