K. Kruse

Single cell transcriptomics reveals functionally specialized vascular endothelium in brain

The paper uses single-cell RNA sequencing to identify reactive endothelial venules in the murine brain, revealing their role in neuroinflammation and ageing.

The effect of motor-induced shaft dynamics on microtubule stability and length

This study investigates how molecular motors affect microtubule stability and length through tubulin exchange along the shaft, revealing novel insights into microtubule network regulation.

Motor usage imprints microtubule stability in the shaft

The paper shows that molecular motor activity on microtubules increases their average length and densifies the network, influencing cell polarity through dimer exchange along the shaft.

Pinching the cortex of live cells reveals thickness instabilities caused by Myosin II motors

The paper measures cortical thickness in live cells using magnetic beads and finds it is dynamic and fluctuates due to actomyosin contractility.

Integer topological defects organize stresses driving tissue morphogenesis

The paper shows integer topological defects in myoblasts organize stresses that drive tissue differentiation and morphogenesis.

Buckling of epithelium growing under spherical confinement

This study demonstrates that epithelial monolayers growing under spherical confinement can fold through buckling, showing forces and elastic properties drive the shape change.

A new twist on bacterial motility - Two distinct type IV pili revealed by cryoEM

This study identifies two distinct type IV pili in Thermus thermophilus using cryoEM, revealing their structural differences and functional roles in motility and DNA uptake.

Aurora A depletion reveals centrosome-independent polarization mechanism in C. elegans

The paper shows that C. elegans zygotes can form two posterior PAR-2 domains without centrosomes, revealing a centrosome-independent polarization mechanism.