Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract
M. E. Ortiz Bezara, A. Thurman, A. A. Pezzulo, M. R. Leidinger, J. A. Klesney-Tait, P. H. Karp, P. Tan, C. Wohlford-Lenane, P. B. McCray, D. K. Meyerholz
This study examines ACE2 protein expression in the human respiratory tract using single-cell RNA sequencing and immunohistochemistry, finding it highest in sinonasal cavity and alveoli, and not correlated with severe COVID-19 risk factors.
bioRxiv · Apr 22, 2020Cell Biology