Author

P. H. S. Sporn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Nair· 2 shared F. Chen· 2 shared F. J. Gonzalez-Gonzalez· 2 shared G. Beitel· 2 shared G. R. S. Budinger· 2 shared S. M. Casalino-Matsuda· 2 shared A. Yemelyanov· 1 shared H. Abdala-Valencia· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

A. Nair

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 28, 2023

Myeloid Zfhx3 Deficiency Protects Against Hypercapnia-induced Suppression of Host Defense Against Influenza A Virus

S. M. Casalino-Matsuda, F. Chen, F. J. Gonzalez-Gonzalez…·P. H. S. Sporn

The paper shows that Zfhx3 deficiency in myeloid cells protects mice from hypercapnia-induced immune suppression and worsens influenza A virus infection.

DOI 10.1101/2023.02.28.530480

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivFeb 13, 2020

Hypercapnia Suppresses Macrophage Antiviral Activity and Increases Mortality of Influenza A 1 Infection via Akt1

S. M. Casalino-Matsuda, F. Chen, F. J. Gonzalez-Gonzalez…·P. H. S. Sporn

This study shows hypercapnia suppresses macrophage antiviral activity and increases influenza A mortality via Akt1 activation in mice.

DOI 10.4049/jimmunol.2000085

mousebulk RNA-seq

𝕏 PostBluesky