Author

P. H. Sudmant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Physiology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Assay:whole-genome sequencing· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. S. Halgren· 2 shared J. M. Torres-Velarde· 2 shared J. P. Vazquez-Medina· 2 shared S. R. R. Kolora· 2 shared A. Fischer· 1 shared A. Guarracino· 1 shared A. Ingason· 1 shared A. J. Schork· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersEvolutionary Biology

A. S. Halgren

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Global diversity, recurrent evolution, and recent selection on amylase structural haplotypes in humans

D. Bolognini, A. S. Halgren, R. N. Lou, A. Raveane, J. Rocha, A. Guarracino, N. Soranzo, J. Chin, E. Garrison, P. H. Sudmant

This study examines amylase structural haplotypes in humans, finding increased copy numbers in agricultural populations and evidence of recent selection over the last 12,000 years.

bioRxiv · Feb 7, 2024 · PreprintEvolutionary Biology

Hypoxia blunts angiogenic signaling and upregulates the antioxidant system in elephant seal endothelial cells

K. Allen, J. M. Torres-Velarde, J. M. Vazquez, D. D. Moreno-Santillan, P. H. Sudmant, J. P. Vazquez-Medina

This study compares the hypoxic response of elephant seal and human endothelial cells, finding seal cells dampen angiogenic signaling, enhance antioxidant defenses, and maintain mitochondrial function.

bioRxiv · Jul 1, 2023 · PreprintPhysiology

Rapid turnover and evolution of sex-determining regions among Sebastes rockfishes

N. T. B. Sykes, S. R. R. Kolora, P. H. Sudmant, G. L. Owens

The paper identifies diverse sex-determination mechanisms in Sebastes rockfish species using genomic data.

bioRxiv · Jan 19, 2023 · PreprintEvolutionary Biology

The Selection Landscape and Genetic Legacy of Ancient Eurasians

E. K. Irving-Pease, A. Refoyo-Martinez, W. Barrie, A. Ingason, A. Pearson, A. Fischer, K.-G. Sjögren, A. S. Halgren, R. Macleod, F. Demeter, R. A. Henriksen, T. Vimala, H. McColl, A. Vaughn, L. Speidel, , E. Willerslev

This study models ancient Eurasian selection landscapes and shows ancestry-specific genetic risk associations with modern phenotypes.

bioRxiv · Sep 22, 2022Evolutionary Biology

Elephant seal muscle cells adapt to sustained glucocorticoid exposure by shifting their metabolic phenotype

J. M. Torres-Velarde, S. R. R. Kolora, J. I. Khudyakov, D. E. Crocker, P. H. Sudmant, J. P. Vazquez-Medina

This study shows that elephant seal myotubes adapt to sustained glucocorticoid exposure by shifting to glycolysis, altering mitochondrial morphology, and reducing mitochondria-ER interactions without affecting cell viability.

bioRxiv · Feb 5, 2021Physiology