Differential Evasion of Delta and Omicron Immunity and Enhanced Fusogenicity of SARS-CoV-2 Omicron BA.4/5 and BA.2.12.1 Subvariants
P. Qu, J. P. Evans, J. N. Faraone, X. Zou, Y.-M. Zheng, C. Carlin, J. S. Bednash, G. Lozanski, R. K. Mallampalli, L. J. Saif, E. M. Oltz, P. J. Mohler, R. J. Gumina, S.-L. Liu
This study compares the neutralization resistance, infectivity, and fusogenicity of SARS-CoV-2 Omicron BA.4/5 and BA.2.12.1 subvariants to other variants and finds increased resistance and fusogenicity linked to L452 mutations.
bioRxiv · May 16, 2022 · PreprintMicrobiology