Predictive modeling reveals that higher-order cooperativity drives transcriptional repression in a synthetic developmental enhancer
Y. J. Kim, K. Rhee, J. Liu, P. Jeammet, M. A. Turner, S. Small, H. G. Garcia
The paper uses thermodynamic models to show that higher-order cooperativity between transcription factors drives transcriptional repression in a synthetic enhancer.
bioRxiv · Jul 28, 2021Biophysics