Author

K. Rhee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 4 Organism:human· 3 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. A. Saleh· 1 shared A. I. Wong· 1 shared A. Lim· 1 shared A. Sivan· 1 shared B. Selbach· 1 shared C. Coker· 1 shared C. Ostroff· 1 shared C. R. Gurbatri· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

A. A. Saleh

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Transferrin Receptor Targeting Chimeras (TransTACs) for Membrane Protein Degradation

D. Zhang, J. Duque-Jimenez, G. Brixi, F. Facchinetti, K. Rhee, W. W. Feng, P. A. Jänne, X. Zhou

This paper introduces TransTACs, a method for degrading membrane proteins by redirecting them to lysosomal degradation using the transferrin receptor, showing high efficiency across various protein types.

bioRxiv · Aug 10, 2023Bioengineering

Colorectal cancer detection and treatment with engineered probiotics

C. R. Gurbatri, G. Radford, L. Vrbanac, C. Coker, J. Im, S. R. Taylor, Y. Jang, A. Sivan, K. Rhee, A. A. Saleh, T. Chien, F. Zandkarimi, I. Lia, T. R. Lannagan, T. Wang, , T. Danino

This paper demonstrates the use of engineered probiotics to detect and treat colorectal cancer by monitoring their colonization and delivering therapeutic molecules.

bioRxiv · Apr 3, 2023 · PreprintBioengineering

Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis

A. I. Wong, T. Beites, K. A. Planck, S. Li, N. C. Poulton, K. Rhee, D. Schnappinger, S. Ehrt, J. M. Rock

This study identifies cAMP as a key mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis by analyzing the role of the essential adenylate cyclase Rv3645.

bioRxiv · Jul 7, 2022Microbiology

Predictive modeling reveals that higher-order cooperativity drives transcriptional repression in a synthetic developmental enhancer

Y. J. Kim, K. Rhee, J. Liu, P. Jeammet, M. A. Turner, S. Small, H. G. Garcia

The paper uses thermodynamic models to show that higher-order cooperativity between transcription factors drives transcriptional repression in a synthetic enhancer.

bioRxiv · Jul 28, 2021Biophysics

Diet Potentially Drives the Differentiation of Eating Behaviours via Alterations to the Gut Microbiome in Infants

C. Yan, H. Zhao, N. Nayar, K. Rhee, J. Lumeng

The paper investigates how infant formula diets alter gut microbiome composition and short-chain fatty acid production, which may reduce food responsiveness and contribute to eating behaviors linked to obesity.

bioRxiv · Apr 24, 2021 · PreprintMicrobiology

Fate of the M-phase-assembled centrioles during the cell cycle in the TP53;PCNT;CEP215-deleted cells

G. I. Jung, K. Rhee

This study examines how supernumerary centrioles formed in TP53;PCNT;CEP215-deleted cells behave during the cell cycle, finding they cannot function as templates for assembly but can organize microtubules during M phase.

bioRxiv · Sep 14, 2020Cell Biology

Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis

R. S. Jansen, L. Mandyoli, R. Hughes, S. Wakabayashi, J. Pinkham, B. Selbach, K. Guinn, E. J. Rubin, J. C. Sacchettini, K. Rhee

This study identifies Rv3722c as the primary aspartate aminotransferase in Mtb, revealing its role in nitrogen distribution and highlighting it as a potential drug target.

bioRxiv · Sep 26, 2019Microbiology