Author

P. Kunach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Assay:cryo-EM· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Lemoff· 1 shared A. Yakubovska· 1 shared B. A. Nguyen· 1 shared B. K. Shoichet· 1 shared B. Kluve-Beckerman· 1 shared I. S. Knight· 1 shared J. G. Pepe· 1 shared J. I. Irwin· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Lemoff

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Author profile →

2 papers

Recent·Most cited

ATTRv-V30M Type A amyloid fibrils from the heart and nerves exhibit structural homogeneity.

B. A. Nguyen, S. Afrin, A. Yakubovska, V. Singh, J. Vaquer-Alicea, P. Kunach, P. Singh, M. Pekala, Y. Ahmed, M. d. C. Fernandez-Ramirez, L. Cabrera Hernandez, R. Pedretti, P. Bassett, L. Wang, A. Lemoff, , L. Saelices Gomez

This study determines the structure of ATTRv-V30M amyloid fibrils from cardiac and nerve tissues using cryo-EM, finding structural homogeneity across tissues when transthyretin originates from the liver.

bioRxiv · May 14, 2024 · PreprintBiophysics

Docking for molecules that bind in a symmetric stack with SymDOCK

M. S. Smith, I. S. Knight, R. C. Kormos, J. G. Pepe, P. Kunach, M. I. Diamond, S. H. Shahmoradian, J. I. Irwin, W. F. DeGrado, B. K. Shoichet

SymDOCK is a docking method that exploits symmetry in amyloid fibrils to predict ligand stacking, successfully reproducing known structures and predicting a new one before its determination.

bioRxiv · Oct 27, 2023Biophysics