Author

P. Larrous

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

F. Margottin-Goguet· 2 shared M. M. Martin· 2 shared M. Morel· 2 shared R. Matkovic· 2 shared A. Cimarelli· 1 shared A. Lasserre· 1 shared C. Garnier· 1 shared K. Zarrouk· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMicrobiology

F. Margottin-Goguet

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2 papers

Recent·Most cited

Deciphering lentiviral Vpr/Vpx determinants required for HUSH and SAMHD1 antagonism highlights the molecular plasticity of these evolutionary conflicts

P. Larrous, C. Garnier, M. Morel, M. M. Martin, K. Zarrouk, S. Maesen, R. Matkovic, A. Cimarelli, L. Etienne, F. Margottin-Goguet

This study identifies viral determinants in Vpr and Vpx proteins that enable antagonism of SAMHD1 and HUSH, revealing molecular plasticity in lentiviral adaptation to host restrictions.

bioRxiv · Mar 7, 2024Microbiology

Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx

M. M. Martin, R. Matkovic, P. Larrous, M. Morel, A. Lasserre, V. Vauthier, F. Margottin-Goguet

This study identifies how HIV-2 Vpx distinguishes between degrading TASOR and SAMHD1 by interacting with DCAF1, revealing a ternary complex and key Vpx mutants affecting TASOR degradation.

bioRxiv · May 6, 2021Microbiology