Author

P. Leung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Assay:multiome· 1

Frequent Co-Authors

C. Cai· 2 shared A. Eltahla· 1 shared A. Lloyd· 1 shared D. K. Sasmal· 1 shared E. Adams· 1 shared E. Hui· 1 shared E. Keoshkerian· 1 shared F. Luciani· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

C. Cai

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Single cell multi-omics reveals early elevated function and multiple fates within human progenitor exhausted CD8+ T cells

F. Luciani, J. Samir, P. Leung, K. Kedzierska, T. Nguyen, A. Lloyd, C. Cai, R. Bull, E. Keoshkerian, A. Eltahla, T. Peters, S. Gaudieri, M. Gupta, T. Adikari, R. Louie, , J.-L. Palgen

The paper identifies progenitor cells of T-cell exhaustion in acute HCV infection and shows their functional and phenotypic characteristics.

bioRxiv · Sep 9, 2021 · PreprintImmunology

TCR-pMHC bond length controls TCR ligand discrimination

D. K. Sasmal, W. Feng, S. Roy, P. Leung, Y. He, C. Cai, G. Cao, H. Lian, J. Qin, E. Hui, H. Schreiber, E. Adams, J. Huang

This study shows that TCR-pMHC bond length controls TCR ligand discrimination by affecting CD3ζ ITAM phosphorylation and downstream signaling.

bioRxiv · Oct 12, 2018 · PreprintImmunology