P. M. Coen

Physical activity unveils the relationship between mitochondrial energetics, muscle quality and physical function in older adults

This study examines mitochondrial function in older adults with varying physical activity levels, finding that active older adults have mitochondrial capacity similar to younger active individuals, linked to better muscle quality and physical function.

Metabolite profile and mitochondrial energetics characterize poor early recovery of muscle mass following hind limb unloading in old mice

This study identifies mitochondrial dysfunction and metabolic dysregulation as factors underlying poor muscle recovery in old mice after hind limb unloading.