Author

D. P. Kelly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:bulk RNA-seq· 3 Research Focus:metabolism & bioenergetics· 3 Organism:mouse· 3 Organism:human· 2 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Kupai· 1 shared B. E. Windle· 1 shared B. Eap· 1 shared B. H. Goodpaster· 1 shared B. M. Dickson· 1 shared B. M. Oswald· 1 shared B. Schilling· 1 shared C. D. King· 1 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperImmunology

A. Kupai

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

MBNL1 regulates programmed postnatal switching between regenerative and differentiated cardiac states.

L. R. J. Bailey, D. Bugg, I. M. Reichardt, C. D. Ortac, J. Gunaje, R. Johnson, M. J. MacCoss, T. Sakamoto, D. P. Kelly, M. Regnier, J. M. Davis

This study identifies MBNL1 as a regulator of cardiac cell state transitions, showing it controls RNA stability to switch between regenerative and differentiated states.

bioRxiv · Mar 16, 2023Cell Biology

Ketone body metabolism declines with age in mice in a sex-dependent manner

B. Eap, M. Nomura, O. Panda, T. Y. Garcia, C. D. King, J. P. Rose, T. C. Leone, D. P. Kelly, B. Schilling, J. C. Newman

This study shows that ketone body metabolism declines with age in mice, with sex-dependent differences in metabolic responses to a ketogenic diet.

bioRxiv · Oct 5, 2022 · PreprintPhysiology

Ketolysis is a metabolic driver of CD8+ T cell effector function through histone acetylation

K. M. Luda, S. M. Kitchen-Goosen, E. H. Ma, M. J. Watson, L. R. Duimstra, B. M. Oswald, J. Longo, Z. Fu, Z. Madaj, A. Kupai, B. M. Dickson, I. Kaymak, K. Lau, S. Compton, L. M. DeCamp, , R. G. Jones

This study identifies ketone bodies as essential for CD8+ T cell metabolism and effector function through histone acetylation regulation.

bioRxiv · Aug 26, 2022 · PreprintImmunology

Human papilloma virus E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1α/ERRα axis

M. K. Sannigrahi, P. Rajagopalan, L. Lai, X. Liu, V. Sahu, H. Nakagawa, J. B. Jalaly, R. M. Brody, I. M. Morgan, B. E. Windle, X. Wang, P. A. Gimotty, D. P. Kelly, E. A. White, D. Basu

This study shows that HPV E6 reduces mitochondrial antioxidant capacity and therapy resistance in oropharyngeal cancer by suppressing the PGC-1α/ERRα pathway.

bioRxiv · May 4, 2022 · PreprintCancer Biology

Metabolite profile and mitochondrial energetics characterize poor early recovery of muscle mass following hind limb unloading in old mice

X. Zhang, M. B. Trevino, M. Wang, S. J. Gardell, J. E. Ayala, X. Han, D. P. Kelly, B. H. Goodpaster, R. B. Vega, P. M. Coen

This study identifies mitochondrial dysfunction and metabolic dysregulation as factors underlying poor muscle recovery in old mice after hind limb unloading.

bioRxiv · Aug 31, 2017Physiology