Author

P. MACHILLOT

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

C. PICART· 5 shared E. MIGLIORINI· 3 shared V. KHODR· 3 shared C. GAROT· 2 shared G. BETTEGA· 2 shared J. Vollaire· 2 shared V. Josserand· 2 shared A. DECAMBRON· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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5 shared papersBioengineering

C. PICART

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Development of an automated high-content immuno-fluorescence assay of pSmads quantification: proof-of-concept with drugs inhibiting the BMP/TGFbeta pathways

V. KHODR, L. CLAUZIER, P. MACHILLOT, A. SALES, E. MIGLIORINI, C. PICART

The paper develops an automated high-content immunofluorescence assay for pSmad quantification and demonstrates its use in drug testing on biomimetic films.

bioRxiv · Dec 14, 2023 · PreprintBioengineering

3D-printed polymeric scaffolds with optimized architecture to repair a sheep metatarsal critical-size bone defect

C. GAROT, S. Schoffit, C. Monfoulet, P. Machillot, C. DEROY, S. ROQUES, J. VIAL, J. Vollaire, M. Renard, H. GHANEM, H. El-Hafci, A. DECAMBRON, V. Josserand, L. BORDENAVE, G. BETTEGA, , C. PICART

This study develops a 3D-printed scaffold with a polyelectrolyte coating delivering BMP-2 to repair a sheep metatarsal defect, showing optimal bone regeneration with specific scaffold geometry and BMP-2 dose.

bioRxiv · Dec 14, 2022 · PreprintBioengineering

Differential bioactivity of four BMP-family members as function of biomaterial stiffness

A. SALES RAMOS, V. KHODR, P. MACHILLOT, L. FOUREL, A. GUEVARA GARCIA, E. MIGLIORINI, C. ALBIGES RIZO, C. PICART

The paper investigates how different BMP-family members affect cell adhesion and bone differentiation in response to varying biomaterial stiffness.

bioRxiv · Feb 10, 2021Cell Biology

3D printed scaffold combined to 2D osteoinductive coatings to repair a critical-size mandibular bone defect

M. BOUYER, C. GAROT, P. MACHILLOT, J. VOLLAIRE, V. FITZPATRICK, S. MORAND, J. BOUTONNAT, V. JOSSERAND, G. BETTEGA, C. PICART

This study shows that 3D printed PLA scaffolds with reduced BMP-2 doses can effectively repair critical-size mandibular bone defects in mini-pigs, comparable to autografts.

bioRxiv · Dec 8, 2020Bioengineering

High throughput measurements of BMP/BMP receptors interactions using bio-layer interferometry

V. KHODR, P. MACHILLOT, E. MIGLIORINI, J.-b. REISER, C. PICART

The paper measures BMP-BMP receptor interactions using bio-layer interferometry to determine kinetic parameters and affinities for various BMPs and receptors.

bioRxiv · Oct 20, 2020Biophysics