Author

P. Machiraju

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

F. Iqbal· 3 shared S. C. Greenway· 3 shared A. Khan· 2 shared A. Ravandi· 2 shared J. Huang· 2 shared R. Sabouny· 2 shared T. Shutt· 2 shared T. Zhao· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

F. Iqbal

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Reversible Mitochondrial Fragmentation in iPSC-Derived Cardiomyocytes from Children with DCMA, a Mitochondrial Cardiomyopathy

L. Rohani, P. Machiraju, R. Sabouny, G. Meng, S. Liu, T. Zhao, F. Iqbal, A. Ravandi, J. C. Wu, A. Khan, T. Shutt, D. Rancourt, S. C. Greenway

This study uses iPSC-derived cardiomyocytes from DCMA patients to show reversible mitochondrial fragmentation and OPA1 isoform imbalance, suggesting SS-31 as a potential therapy.

Canadian Journal of Cardiology · Apr 1, 2020Peer-reviewedCell Biology

Early Inhibition of Retinoic Acid Signaling Rapidly Generates Cardiomyocytes Expressing Ventricular Markers from Human Induced Pluripotent Stem Cells

P. Machiraju, J. Huang, F. Iqbal, Y. Liu, X. Wang, C. Bousman, S. C. Greenway

This study shows that inhibiting retinoic acid signaling early in differentiation rapidly generates ventricular-like cardiomyocytes from human iPSCs with higher MLC2V expression.

bioRxiv · Nov 26, 2019 · PreprintCell Biology

SS-31 Reverses Mitochondrial Fragmentation in Fibroblasts from Patients with DCMA, a Mitochondrial Cardiomyopathy

P. Machiraju, X. Wang, R. Sabouny, J. Huang, T. Zhao, F. Iqbal, M. King, D. Prasher, A. Lodha, A. Ravandi, B. Argiropoulos, D. Sinasac, A. Khan, T. Shutt, S. C. Greenway

This study shows that SS-31 reverses mitochondrial fragmentation and increases ROS in DCMA fibroblasts, suggesting it as a potential therapy for this mitochondrial cardiomyopathy.

bioRxiv · Jun 17, 2019Cell Biology