Animal Behavior & CognitionbioRxivPreprint
Sex-dependent effects of CYP46A1 overexpression on cognitive function during aging
M. Latorre-Leal, P. Rodriguez-Rodriguez, L. Franchini…·S. Maioli
This study shows that CYP46A1 overexpression improves cognitive function in aged female mice but harms male mice, with sex-specific effects on synaptic function and neurodegeneration markers.
DOI 10.1101/2021.04.23.441050