Author

P. Önnerfjord

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Turkiewicz· 1 shared A. Wall· 1 shared C. J. Philp· 1 shared C. McLean· 1 shared C. P. Winlove· 1 shared E. Folkesson· 1 shared G. E. Pavlovskaya· 1 shared H. Isaksson· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. Turkiewicz

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2 papers

Recent·Most cited

Mineral crystal thickness in calcified cartilage and subchondral bone in healthy and osteoarthritic knees

M. A. J. Finnilä, S. Das Gupta, M. J. Turunen, I. Kestilä, A. Turkiewicz, V. Lutz-Bueno, E. Folkesson, M. Holler, N. Ali, V. Hughes, H. Isaksson, J. Tjörnstrand, P. Önnerfjord, M. Guizar-Sicairos, S. Saarakkala, M. Englund

The paper measures mineral crystal thickness in calcified cartilage and subchondral bone of healthy and osteoarthritic knees, finding increased thickness in the unloaded lateral compartment and decreased thickness in subchondral bone with OA severity.

bioRxiv · Jun 15, 2021 · PreprintBiophysics

Matrix-Bound Growth Factors are Released upon Cartilage Compression by an Aggrecan-Dependent Sodium Flux that is Lost in Osteoarthritis

S. J. Keppie, J. C. Mansfield, X. Tang, C. J. Philp, H. K. Graham, P. Önnerfjord, A. Wall, C. McLean, C. P. Winlove, M. J. Sherratt, G. E. Pavlovskaya, T. L. Vincent

This paper identifies a novel repair mechanism in cartilage where aggrecan-dependent sodium flux, triggered by mechanical injury, releases growth factors that promote tissue regeneration, which is impaired in osteoarthritis.

bioRxiv · Jan 31, 2021Cell Biology